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Epothilones
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
CRIP1
ANO1
DLK1
TXNIP
LPL
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Pathway Enrichment
Most Correlated Biogroups
cytosol
organic cyclic compound binding
heterocyclic compound binding
regulation of nitrogen compound metabolic process
organic cyclic compound metabolic process
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Curated Studies
Most Correlated Studies
Invasive breast adenocarcinomas before Ixabepilone or Paclitaxel treatment
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature
Most Relevant Literature
Co-cultivation of Sorangium cellulosum strains affects cellular growth and biosynthesis of secondary…
Altered TUBB3 expression contributes to the epothilone response of mitotic cells.
The epothilones: new therapeutic agents for castration-resistant prostate cancer.
Epothilones in prostate cancer.
New epothilone congeners from Sorangium cellulosum strain So0157-2.
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Clinical Trials
Most Relevant Clinical Trials
Epothilone in Recurrent Glioblastoma Patients
Epothilone B in Treating Patients With CNS Metastases From Breast Cancer
Epothilone D as Second-Line Treatment for Patients With Advanced or Metastatic Refractory Colorectal…
A Trial to Evaluate Epothilone D in Patients With Advanced Solid Tumors
Epothilone ZK-219477 in Treating Patients With Recurrent Glioblastoma
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