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IRAK-1
(gene)
Summary
General Info
Body Atlas
Most Correlated Tissues
Parotid gland
Natural killer cell of peripheral blood
Dendritic (plasmacytoid) cell
Microglial cell
Plasma cell of spleen
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Disease Atlas
Most Correlated Diseases
Placental insufficiency
Fetal growth restriction
Caseating tuberculoid granuloma
Disorder of uterus
Tularemia
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Most Correlated Compounds
Histone Deacetylase Inhibitors
SOST protein, human
pyroxamide
JM 3100
phenethyl isothiocyanate
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Knockdown Atlas
Most Correlated Gene Perturbations
MIR520G
PHKB
LCP2
EDA
TMED9
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Curated Studies
Most Correlated Studies
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Literature
Most Relevant Literature
IRAK1 and IRAK4 as emerging therapeutic targets in hematologic malignancies.
Nonhematopoietic IRAK1 drives arthritis via neutrophil chemoattractants.
IRAK1 inhibition blocks the HIV-1 RNA mediated pro-inflammatory cytokine response from microglia.
Pharmacological inhibition of IRAK1 and IRAK4 prevents endothelial inflammation and atherosclerosis …
Effect of sodium butyrate regulating IRAK1 (interleukin-1 receptor-associated kinase 1) on visceral …
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Clinical Trials
Most Relevant Clinical Trials
A Phase 1/2 Study of Oral IRAK-4 Inhibitor CA-4948 in Combination With Pembrolizumab Following Stere…
IRAK 4 Inhibitor (PF-06650833) in Hospitalized Patients With COVID-19 Pneumonia and Exuberant Inflam…
TLR Polymorphism, ASO and Beta-hemolytic Group A Streptococcus Infections in ADHD: an Observational …
Mathematical Modeling of the Acute Inflammatory Response Following Injury
The Effects of Moxibustion on Ulcerative Colitis
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