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QuickView for JAK1 (gene)


Body Atlas

Most Correlated Tissues

  1. Basophil of peripheral blood
  2. T Lymphocyte (regulatory) of peripheral blood
  3. Natural killer cell of peripheral blood
  4. Neutrophil of bone marrow
  5. T Lymphocyte (CD4+) of peripheral blood
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Disease Atlas

Most Correlated Diseases

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Pharmaco Atlas

Most Correlated Compounds

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Knockdown Atlas

Most Correlated Gene Perturbations

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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Synthesis and structure-activity relationship studies of 1,5-isomers of triazole-pyrrolopyrimidine a…
  2. Infectious Bronchitis Virus Nsp14 Degrades JAK1 to Inhibit the JAK-STAT Signaling Pathway in HD11 Ce…
  3. JAK1 signaling in dendritic cells promotes peripheral tolerance in autoimmunity through PD-L1-mediat…
  4. IL-32 promotes the occurrence of atopic dermatitis by activating the JAK1/microRNA-155 axis.
  5. Pharmacophore modeling of JAK1: A target infested with activity-cliffs.
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Clinical Trials

Most Relevant Clinical Trials

  1. Selinexor in Myelofibrosis Refractory or Intolerant to JAK1/2 Inhibitors
  2. Dual JAK1/TYK2 Inhibitor for Cicatricial Alopecia
  3. Study of Baricitinib, a JAK1/2 Inhibitor, in Chronic Graft-Versus-Host Disease After Allogeneic Hema…
  4. JAK1 Inhibitor With Medicated Topical Therapy in Adolescents With Atopic Dermatitis
  5. A Phase II Study of Oral JAK1/JAK2 Inhibitor INC424 in Adult Patients With Relapsed/Refractory Class…
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