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LMNA
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Body Atlas
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Curated Studies
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Embryonic stem and primordial germ cells derived and maintained in different culture conditions
Targeted gene correction of LMNA mutations in patient-specific iPSCs
Fibroblasts overexpressing prelamin A/progerin + treated with farnesyltransferase inibitor L-744832
Skin fibroblast cells from cardiomyopathy subjects with LMNA S143P mutation
Heart tissue from dilated cardiomyopathy subjects
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Literature
Most Relevant Literature
A-type lamins involvement in transport and implications in cancer?
Mice harboring a R133L heterozygous mutation in LMNA exhibited ectopic lipid accumulation, aging, an…
Diurnal shift of mouse activity by the deficiency of an ageing-related gene Lmna.
The LMNA p.R541C mutation causes dilated cardiomyopathy in human and mice.
Nucleoplasmic lamin C rapidly accumulates at sites of nuclear envelope rupture with BAF and cGAS.
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Clinical Trials
Most Relevant Clinical Trials
A Rollover Study of ARRY-371797 in Patients With LMNA-Related Dilated Cardiomyopathy
A Study of ARRY-371797 in Patients With LMNA-Related Dilated Cardiomyopathy
Modifying Factors in Striated Muscle Laminopathies
The Deep Phenotype of Lamin A/C Cardiomyopathy
Study of Cortisol Metabolism in Familial Partial Lipodystrophy Type 2
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