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QuickView for MLH1 (gene)


Body Atlas

Most Correlated Tissues

  1. Testes
  2. Skeletal muscle
  3. Pituitary gland
  4. Jejunum
  5. Heart
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Disease Atlas

Most Correlated Diseases

  1. Bacterial sepsis of newborn
  2. Hypertrophic cardiomyopathy
  3. Social environment related disease
  4. Bacterial pneumonia
  5. Disease due to Gammaherpesvirinae
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Pharmaco Atlas

Most Correlated Compounds

  1. 5-azacytosine
  2. 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one
  3. Nickel
  4. tetrachloroisophthalonitrile
  5. DIG-mithramycin SK
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. hsa-miR-34a-5p
  2. SPS100
  3. YHR097C
  4. USV1
  5. PBI2
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Tissue-specific reduction in MLH1 expression induces microsatellite instability in intestine of Mlh1…
  2. Mlh1 heterozygosity and promoter methylation associates with microsatellite instability in mouse spe…
  3. MLH1 mediates cytoprotective nucleophagy to resist 5-Fluorouracil-induced cell death in colorectal c…
  4. Expressing MLH1 in HCT116 cells increases cellular resistance to radiation by activating the PRKAC.
  5. Molecular Analysis of an Intestinal Neuroendocrine/Non-neuroendocrine Neoplasm (MiNEN) Reveals MLH1 …
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Clinical Trials

Most Relevant Clinical Trials

  1. The Impact of Epigenetic MMRd in Endometrial carcinomas-a Real World Study
  2. Patogenic Mutation in 5 Genes
  3. Studying Tissue Samples From Patients With Stage II Colon Cancer Treated on Clinical Trial CLB-9581
  4. Cascade Testing in Families With Newly Diagnosed Hereditary Breast and Ovarian Cancer Syndrome
  5. Nivolumab in Preventing Colon Adenomas in Participants With Lynch Syndrome and a History of Partial …
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