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MTHFD2
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Summary
General Info
Body Atlas
Most Correlated Tissues
T Lymphocyte (regulatory) of peripheral blood
Eosinophil of peripheral blood
Hematopoietic stem cell of bone marrow
Granulocyte-macrophage progenitor cell of bone marrow
Microglial cell
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Disease Atlas
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Knockdown Atlas
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Curated Studies
Most Correlated Studies
Acute myeloid leukemia MOLM-14 cells with MTHFD2 shRNA knockdown
L1000 CMAP - Hepatocellular carcinoma Hep G2 cells with shRNA-mediated gene knockdown (1 of 2)
L1000 CMAP - Adipose MSC ASC52telo cells with shRNA-mediated gene knockdown
Human aortic endothelial cells with MTHFD2 siRNA knockdown
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Literature
Most Relevant Literature
MTHFD2 suppresses glioblastoma progression via the inhibition of ERK1/2 phosphorylation.
Xanthine Derivatives Reveal an Allosteric Binding Site in Methylenetetrahydrofolate Dehydrogenase 2 …
Metabolic collateral lethal target identification reveals MTHFD2 paralogue dependency in ovarian can…
Association of maternal MTHFD1 and MTHFD2 gene polymorphisms with congenital heart disease in offspr…
Detection and characterisation of novel alternative splicing variants of the mitochondrial folate en…
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Clinical Trials
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There were no clinical trials for MTHFD2
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