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QuickView for NLRP3 (gene)


Body Atlas

Most Correlated Tissues

  1. Basophil of peripheral blood
  2. Macrophage of peripheral blood
  3. Monocyte of peripheral blood
  4. Hematopoietic stem cell of bone marrow
  5. Mononuclear cell of peripheral blood
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Disease Atlas

Most Correlated Diseases

  1. Amyloidosis
  2. Upper respiratory infection
  3. Arthropathy
  4. Fungal keratitis
  5. Fusarium infection
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Pharmaco Atlas

Most Correlated Compounds

  1. tat Gene Products, Human Immunodeficiency Virus
  2. Disopyramide
  3. Bretylium Tosylate
  4. amyloid beta-protein (1-42)
  5. Molindone
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. MIR10B
  2. IRAK4
  3. VAV2
  4. ETS1
  5. BAZ1B
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7-NLRP3 interaction.
  2. The NLRP3 inflammasome modulates tau pathology and neurodegeneration in a tauopathy model.
  3. CCDC50 suppresses NLRP3 inflammasome activity by mediating autophagic degradation of NLRP3.
  4. Ginkgolide B inactivates the NLRP3 inflammasome by promoting autophagic degradation to improve learn…
  5. NLRP3 Is Involved in Neutrophil Mobilization in Experimental Periodontitis.
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Clinical Trials

Most Relevant Clinical Trials

  1. Effect of Fasting on the NLRP3 Inflammasome
  2. Quantification of NLRP3 (rs4612666) and CARD8 Gene (rs2043211) in Generalized Chronic Periodontitis …
  3. INFLAmmasomes NLRP3 in Platelets and Leukocytes During SEPSIS in Intensive Care Unit
  4. Change of NLRP3 Inflammasome Expression Level, Symptoms, and Functional Status in HFpEF Patients Tre…
  5. Epigenetic Analysis of Regulation of the Inflammasome-activating NLRP3 Gene in Monocytes From Atrial…
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