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Notch 1
Summary
General Info
Curated Studies
Most Correlated Studies
Aortic valve interstitial cells treated with gamma-secretase/Notch signaling inhibitor
Inhibition of Notch signaling in T-cell response
Breast cancer HCC1599 cells with DMSO (NOTCH-On) or GSI compound E washouts (Notch-Off)
Naive T cell responses to Notch signalling
Notch signaling activation and inactivation in colorectal tumors
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Literature
Most Relevant Literature
NOTCH1 Mutations Inhibit Tumor Growth in the Esophageal Epithelium.
NOTCH1-Related Leukoencephalopathy: A Novel Variant and Literature Review.
CAD204520 Targets NOTCH1 PEST Domain Mutations in Lymphoproliferative Disorders.
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth.
NOTCH1 loss of the TAD and PEST domain: An antimorph?
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Clinical Trials
Most Relevant Clinical Trials
A Biological Study of Resveratrol's Effects on Notch-1 Signaling in Subjects With Low Grade Gastroin…
A Phase 1/2 Study CB-103 With or Without Venetoclax in Patients With NOTCH ACC
Notched Noise Therapy for Suppression of Tinnitus
A Study Of AL101 In Patients With Adenoid Cystic Carcinoma (ACC) Bearing Activating Notch Mutations
Notch Inhibitor in Advanced Cancer
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