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QuickView for PARP-1 (gene)


Body Atlas

Most Correlated Tissues

  1. B lymphocyte (IgM memory) of spleen
  2. B lymphocyte (naive) of spleen
  3. Plasma cell of spleen
  4. Tonsil
  5. Olfactory bulb
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Disease Atlas

Most Correlated Diseases

  1. Xeroderma pigmentosum
  2. Disease due to Orthopoxvirus
  3. Measles
  4. Wegener's granulomatosis
  5. Systemic inflammatory response syndrome
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Pharmaco Atlas

Most Correlated Compounds

  1. 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
  2. Aminoglutethimide
  3. 5-(6)-carboxyfluorescein diacetate succinimidyl ester
  4. Benzofurans
  5. Dipyrone
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. Mir129
  2. Zfp281
  3. TMEM127
  4. PARP1
  5. RET
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. The role of PARP1 in neurodegenerative diseases and aging.
  2. Deacetylation-dependent regulation of PARP1 by SIRT2 dictates ubiquitination of PARP1 in oxidative s…
  3. Nuclear Tkt promotes ischemic heart failure via the cleaved Parp1/Aif axis.
  4. An unexpected role for BAG3 in regulating PARP1 ubiquitination in oxidative stress-related endotheli…
  5. STING modulates necrotic cell death in CD4 T cells via activation of PARP-1/PAR following acute syst…
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Clinical Trials

Most Relevant Clinical Trials

  1. Expression of PARP-1 in Multiple Sclerosis Patients
  2. In Vivo PARP-1 Expression With 18F-FTT PET/CT in Pancreatic Cancer
  3. In Vivo PARP-1 Expression With 18F-FluorThanatrace PET/CT in Patients With Pheochromocytoma and Para…
  4. Evaluating in Vivo PARP-1 Expression With 18F-FluorThanatrace Positron Emission Tomography (PET/CT) …
  5. Study of the Poly (ADP-ribose) Polymerase-1 (PARP-1) Inhibitor BSI-201 in Patients With Newly Diagno…
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