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PI3Kα
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Curated Studies
Most Correlated Studies
Left ventricles of mice with activated PIK3A 7d post transverse aortic constriction (TAC)
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Literature
Most Relevant Literature
Precision Targeting of Mutant PI3Kα.
A New Wave of PI3Kα Inhibitors.
Development of PI3Kα inhibitors for tumor therapy.
A small-molecule PI3Kα activator for cardioprotection and neuroregeneration.
Dissecting the Interaction Fingerprints and Binding Affinity of BYL719 Analogs Targeting PI3Kα.
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Clinical Trials
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First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Advanced So…
First-in-Human Study of STX-478 as Monotherapy and in Combination With Other Antineoplastic Agents i…
A Phase 1b/2 Study of Serabelisib in Combination With Canagliflozin in Patients With Advanced Solid …
Study of CYH33 in Combination With Olaparib an Oral PARP Inhibitor in Patients With Advanced Solid T…
First-in-Human Study of RLY-5836 in Advanced Breast Cancer and Other Solid Tumors
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