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Correlation Engine 2.0
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QuickView for Pten (gene)


Body Atlas

Most Correlated Tissues

  1. Cerebellar hemisphere
  2. Leukocyte (polymorphonuclear) of peripheral blood
  3. Cerebellar vermis
  4. Cerebellum
  5. Peritoneum
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Disease Atlas

Most Correlated Diseases

  1. VATER association
  2. Macrocephaly
  3. Bacterial infection due to Bacillus
  4. Disease caused by parasite
  5. Brain cancer
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Pharmaco Atlas

Most Correlated Compounds

  1. CCI 779
  2. Extracellular Matrix Proteins
  3. 2-(4-(pyridin-4-yl-1-(2,2,2-trifluoroethyl)-1H-pyrazol-3-yl)phenoxymethyl)quinoline succinic acid
  4. benazepril
  5. PCI 24781
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. gld-1
  2. PRKAR2B
  3. OMD
  4. B2M
  5. PNPLA2
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Regulation of the tumor suppressor PTEN in triple-negative breast cancer.
  2. Prognostic value of PTEN in de novo diagnosed metastatic prostate cancer.
  3. PTEN Regulates Dendritic Arborization by Decreasing Microtubule Polymerization Rate.
  4. Molecular dynamic study on PTEN frameshift mutations in breast cancer provide c2 domain as a potenti…
  5. Circling back to PTEN: Fumarate inhibits canonical tumor suppressor.
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Clinical Trials

Most Relevant Clinical Trials

  1. Partial PTEN Deletion in Breast Cancer
  2. Access to Resources for Patients With PTEN Hamartoma Tumor Syndrome
  3. TAS-117 in Patients With Advanced Solid Tumors Harboring Germline PTEN Mutations
  4. RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome
  5. Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations
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