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RAS GTPase
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Curated Studies
Most Correlated Studies
Perturbations in Ras/cAMP signal transduction in yeast
Breast cancer MDA-MB-231 cells treated with RHO GTPase inhibitor DC-RC-063
Anaplastic thyroid carcinoma 8505c cells expressing SOD3 and cultured in long-term
Malignant peripheral nerve sheath tumor cells 90-8TL overexpressing SUZ12 or treated with JQ1
T-ALL cell lines from bone marrow with transduced attenuated KRAS and acquired KRAS mutations
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Literature
Most Relevant Literature
Molecular and phenotypical findings of a novel de novo SYNGAP1 gene variant in an 11-year-old Irania…
Leep2A and Leep2B function as a RasGAP complex to regulate macropinosome formation.
Real-Time Monitoring of RAS Activity Using In Vitro and In-Cell NMR Spectroscopy.
AIDA-1/ANKS1B Binds to the SynGAP Family RasGAPs with High Affinity and Specificity.
Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenes…
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Clinical Trials
Most Relevant Clinical Trials
Evaluation of GTPase Inhibition by Post-operative Intravenous Ketorolac in Ovarian Cancer Patients
Refametinib(BAY86-9766) in RAS Mutant Hepatocellular Carcinoma (HCC)
Refametinib in Combination With Sorafenib in RAS Mutant Hepatocellular Carcinoma (HCC)
R115777 to Treat Children With Neurofibromatosis Type 1 and Progressive Plexiform Neurofibromas
PURO Panitumumab in Combination With Gemcitabine/Cisplatin in Advanced Urothelial Cancer
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