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SCA2
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Bursa cells cultured with Sca2+ or Sca2- stromal cells
Neurons from iPSCs generated from dermal fibroblasts/PBMCs of spinocerebellar ataxia 2 and 3 patient
Cerebella, midbrains and livers from 6mo, 12mo and 24mo old ATXN2 knockout mice
Cerebellum, brainstem and liver expression profiles of ATXN2-CAG42 knock-in mice
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Literature
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ATXN2 intermediate expansions in amyotrophic lateral sclerosis.
Missense mutation in ATXN2 gene (c.2860C > T) in an amyotrophic lateral sclerosis patient with aggre…
The RNA-binding protein and stress granule component ATAXIN-2 is expressed in mouse and human tissue…
Ataxin-2 gene: a powerful modulator of neurological disorders.
Antagonistic roles for Ataxin-2 structured and disordered domains in RNP condensation.
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Clinical Trials
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RISCA : Prospective Study of Individuals at Risk for SCA1, SCA2, SCA3, SCA6, SCA7
Safety and Tolerability of Lithium in Spinocerebellar Ataxia 2 (SCA2)
The EUROSCA Natural History Study
Clinical Trial With Riluzole in Spinocerebellar Ataxia Type 2 (ATRIL)
Contribution of New Generation Oxford Nanopore-type High-throughput Sequencing in the Diagnostic Str…
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