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SEB superantigens
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
CXCL9
CXCL10
ZBED2
GZMB
RRM2
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Pathway Enrichment
Most Correlated Biogroups
response to stress
immune response
PILON_KLF1_TARGETS_DN
PUJANA_BRCA1_PCC_NETWORK
DODD_NASOPHARYNGEAL_CARCINOMA_DN
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Curated Studies
Most Correlated Studies
CD4+ memory T cells are preferential targets for bystander activation and apoptosis
Spleen from PBS or bortezomib pretreated mice exposed to Staphylococcal Enterotoxin B
Epithelial cells EPCAM1+ CD45- of RETNLB KO and IL4R F709 mut mice treated with Ova + SEB
Hearts, kidneys, lungs, PBMCs, and spleens of mice treated with staphylococcal enterotoxin B (SEB)
B cell and PBMC co-cultures stimulated with anti-IgM and superantigens
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Literature
Most Relevant Literature
Development of nanobodies against Staphylococcus enterotoxin B through yeast surface display.
Determination of C5a in murine models of staphylococcal enterotoxin B-induced toxic shock.
Comparison of immunoreactivity of staphylococcal enterotoxin B mutants for use as toxin surrogates.
Amygdaloid signature of peripheral immune activation by bacterial lipopolysaccharide or staphylococc…
Staphylococcal enterotoxin B-derived haptens promote sensitization.
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Clinical Trials
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Safety, Pharmacokinetics, and Pharmacodynamics of BIRT 2584 XX Administered as Multiple Doses and Sa…
Phase I STEBVax in Healthy Adults
Interleukin-4Ra Blockade by Dupilumab Decreases Staphylococcus Colonization and Increases Microbial …
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