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QuickView for SM-164 (compound)


Genetic Markers

Most Correlated Genes

  1. TNFRSF6B
  2. SPRR1A
  3. CCL20
  4. CCL22
  5. CXCL10
Explore Genetic Markers Results

Pathway Enrichment

Most Correlated Biogroups

  1. MURARO_PANCREAS_DUCTAL_CELL
  2. HALLMARK_TNFA_SIGNALING_VIA_NFKB
  3. ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
  4. TRAVAGLINI_LUNG_OLR1_CLASSICAL_MONOCYTE_CELL
  5. BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
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Curated Studies

Most Correlated Studies

  1. MDA-MB-231 parental and xenograft tumor cells treated with Smac mimetic SM-164
  2. Colorectal cancer HT29 cells with different treatments to induce or inhibit necroptosis
  3. Colon adenocarcinoma HT-29 cells treated with TNF alone or in combination with SM-164 and zVAD
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Literature

Most Relevant Literature

  1. Inhibitor of apoptosis proteins antagonist SM164 ameliorates experimental MPO-ANCA-associated vascul…
  2. Enhanced activity of AZD5582 and SM-164 in rabies virus glycoprotein-lactoferrin-liposomes to downre…
  3. The IAP Antagonist SM-164 Eliminates Triple-Negative Breast Cancer Metastasis to Bone and Lung in Mi…
  4. Therapy of Smac mimetic SM-164 in combination with gemcitabine for pancreatic cancer.
  5. Smac-mimetic compound SM-164 induces radiosensitization in breast cancer cells through activation of…
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Clinical Trials

Most Relevant Clinical Trials

  1. Use of SMS and Interactive Reminders to Improve Timely Immunization Coverage
  2. A Phase III Study of SM-13496 in Patients With Bipolar I Depression.
  3. Smoking Cessation Via Text Messaging: Feasibility Testing of Stop My Smoking USA
  4. Promoting Tobacco Control and Smoking Cessation in Workplaces [Phase I]
  5. Multi-Center Clinical Evaluation of Two Reusable Soft Contact Lenses
Explore Clinical Trials Results
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