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SRC 2
NextBio Summary
General Info
Curated Studies
Most Correlated Studies
Liver expression profiles in WT and SRC-2 null mice
Uteri of ovariectomized Ncoa2 (SRC-2) knockout mice treated with progesterone
Prostates with prostate-specific heterozygous PTEN and SRC-2 overexpression
Prostate epithelial cancer cells overexpressing MYC, HRAS G12V, SRC, or ERBB2 mutant NeuT
Breast cancer LY-2 cells (endocrine resistant) with SRC-1 shRNA and treated with 4-hydroxytamoxifen
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Literature
Most Relevant Literature
Hypothalamic steroid receptor coactivator-2 regulates adaptations to fasting and overnutrition.
Independent prognostic impact of plasma NCOA2 alterations in metastatic castration-resistant prostat…
Androgen deprivation-induced NCoA2 promotes metastatic and castration-resistant prostate cancer.
A Sleeping Beauty mutagenesis screen reveals a tumor suppressor role for Ncoa2/Src-2 in liver cancer…
Association of NCOA2 gene polymorphisms with obesity and dyslipidemia in the Chinese Han population.
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Clinical Trials
Most Relevant Clinical Trials
Neoadjuvant Phase 2 Study Comparing the Effects of AR Inhibition With/Without SRC or MEK Inhibition …
Comparison of Biomarker Modulation by Inhibition of EGFR and/or SRC Family
SRC Inhibition as a Potential Target for Parkinson's Disease Psychosis
Psma Intensity Can be Altered by Androgen and Phospho-SrC Obstruction
PH I SRC Kinase, Dasatinib Combo Paclitaxel & Carboplatin in Pts w Ovarian, Peritoneal, & Tubal Canc…
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