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QuickView for STAT1 (gene)


Body Atlas

Most Correlated Tissues

  1. T Lymphocyte (regulatory) of peripheral blood
  2. Natural killer cell of peripheral blood
  3. T Lymphocyte (CD4+) of peripheral blood
  4. Macrophage of peripheral blood
  5. Neutrophil of bone marrow
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Disease Atlas

Most Correlated Diseases

  1. Disease due to Arenavirus
  2. Polymyositis
  3. Measles
  4. Disease due to Trypanosomatidae
  5. Mycobacteriosis
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Pharmaco Atlas

Most Correlated Compounds

  1. Cyclizine
  2. 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one
  3. IFN-alpha21a(1-95), IFN-alpha2c(96-165) fusion protein
  4. Polysaccharides
  5. glutarimide
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. MEF2B
  2. PCSK9
  3. CLPP
  4. PIK3C3
  5. CACYBP
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. An inhibitory effect on the nuclear accumulation of phospho-STAT1 by its unphosphorylated form.
  2. Poxviruses and paramyxoviruses use a conserved mechanism of STAT1 antagonism to inhibit interferon s…
  3. Gain-of-function STAT1 mutation and visceral leishmaniasis.
  4. Unique aspects of IFN-γ/STAT1 signaling in neurons.
  5. STAT1 signaling protects self-reactive T cells from control by innate cells during neuroinflammation…
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Clinical Trials

Most Relevant Clinical Trials

  1. Expanded Access Use of Itacitinib to Treat a Single Patient With STAT1 Gain of Function (GOF) Diseas…
  2. Recombinant Interferon Alfa-2b in Treating Patients With Melanoma
  3. In Vitro Evaluation of a Novel Drug on Airway Epithelial Cells Obtained From Participants With Sever…
  4. Genetic Analysis of Immune Disorders
  5. Genetic Basis of Primary Immunodeficiencies
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