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TSC1/TSC2 complex
Summary
General Info
Curated Studies
Most Correlated Studies
Immortalized MEFs with TSC1 or TSC2 deletions treated with rapamycin
Gene expression in cortical tubers isolated from tuberous sclerosis complex patients
Transcript Profiling of tuberous sclerosis complex (TSC) Tumor Fibroblasts
Neural progenitor cells from tuberous sclerosis complex patient with TSC2 mutation
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Literature
Most Relevant Literature
Deficient TSC1/TSC2-complex suppression of SOX9-osteopontin-AKT signalling cascade constrains tumour…
TRIM31 is upregulated in hepatocellular carcinoma and promotes disease progression by inducing ubiqu…
TBC1D7 Is a Core Subunit of the TSC1-TSC2 Complex.
Identification of regions critical for the integrity of the TSC1-TSC2-TBC1D7 complex.
TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1.
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Clinical Trials
Most Relevant Clinical Trials
Everolimus for Cancer With TSC1 or TSC2 Mutation
Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Altera…
Everolimus in Patients With Advanced Solid Malignancies With TSC1, TSC2, NF1, NF2, or STK11 Mutation…
Characterization of Patients With Tuberous Sclerosis Complex, Lymphangioleiomyomatosis and Angiomyol…
Biomarkers for Tuberous Sclerosis Complex (BioTuScCom)
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