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QuickView for Tofacitinib (compound)


Genetic Markers

Most Correlated Genes

  1. HBB
  2. PM20D1
  3. HP
  4. CUX2
  5. NNMT
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Pathway Enrichment

Most Correlated Biogroups

  1. cytosol
  2. response to organic substance
  3. response to stress
  4. MODULE_5
  5. REACTOME_IMMUNE_SYSTEM
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Curated Studies

Most Correlated Studies

  1. Skin biopsies of psoriasis patients treated with tofacitinib for varying timepoints
  2. Dermal papilla cells from donors in spheres treated with tofacitinib or ruxolitinib
  3. Skin post-5/6wk or 12wk of treatment with IL-15 pathway inhibitors or PBS following alopecia graft
  4. Skin from alopecia areata allografts treated with ruxolitinib or tofacitinib
  5. Scalp biopsies of alopecia areata patients treated with tofacitinib
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Literature

Most Relevant Literature

  1. Safety and effectiveness of tofacitinib in ulcerative colitis: Data from TOFA-UC, a SN-IBD study.
  2. Tofacitinib-induced eosinophilia.
  3. Tofacitinib in pyoderma gangrenosum - A case series.
  4. Microneedle Mediated Iontophoretic Delivery of Tofacitinib Citrate.
  5. Tofacitinib in dermatology: a potential opportunity for topical applicability through novel drug-del…
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Clinical Trials

Most Relevant Clinical Trials

  1. Tofacitinib in Depression (TIDE)
  2. Study of Tofacitinib in Refractory Dermatomyositis
  3. Tofacitinib for Immune Skin Conditions in Down Syndrome
  4. Tofacitinib in Recurrent GBM Patients
  5. Comparison of Tofacitinib and Methotrexate in Takayasu's Arteritis
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