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WRN
(gene)
Summary
General Info
Body Atlas
Most Correlated Tissues
Granulocyte-macrophage progenitor cell of bone marrow
Hematopoietic stem cell of bone marrow
Dendritic (plasmacytoid) cell
T Lymphocyte (regulatory) of peripheral blood
Basophil of peripheral blood
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Literature
Most Relevant Literature
The identification of a novel mutation (p.I223fs) in WRN associated with Werner syndrome.
Combination of untargeted and targeted proteomics for secretome analysis of L-WRN cells.
WRN exonuclease imparts high fidelity on translesion synthesis by Y family DNA polymerases.
WRN Is a Promising Synthetic Lethal Target for Cancers with Microsatellite Instability (MSI).
Identification of 2-Sulfonyl/Sulfonamide Pyrimidines as Covalent Inhibitors of WRN Using a Multiplex…
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Clinical Trials
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Studying Tissue Samples From Patients With Stage II Colon Cancer Treated on Clinical Trial CLB-9581
Combination of HX008 And Niraparib in GErm-line-mutAted Metastatic Breast Cancer
Lurbinectedin With or Without Irinotecan in Treating Patients With Relapsed or High Risk Metastatic …
Study of SBRT/Olaparib Followed by Pembrolizumab/Olaparib in Gastric Cancers
A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001…
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