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allosteric regulation
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Genetic Markers
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Curated Studies
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Glioblastoma stem-like cells treated with MALT1 allosteric inhibitor mepazine
Diffuse large B-cell lymphoma Karpas-422 cells treated with allosteric PRC2 inhibitor EED226
Uveal melanoma 92.1 cells treated with FR900359
Breast adenocarcinoma MCF7 and colon carcinoma HCT116 cells treated w/ small molecule AKT inhibitor
Hearts from mice expressing cardiac-specific PFK2 kinase- or phosphatase-deficient mutation
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Literature
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Involvement of the β3-α3 loop of the proline dehydrogenase domain in allosteric regulation of membra…
Structure and mechanisms of Escherichia coli aspartate transcarbamoylase.
Hemoglobin allostery: new views on old players.
Charge profile analysis reveals that activation of pro-apoptotic regulators Bax and Bak relies on ch…
Differential regulation of hexameric and dodecameric hemocyanin from A. leptodactylus.
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Clinical Trials
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Role of SLURP-1 in Melanoma and Melanoma Stem Cells
Study of MK 2206 in Patients With Relapsed or Refractory Diffuse Large B Cell Lymphoma
Studies of Sulfur Metabolism in Humans
Modulatory Effects of Active Drugs on the Endocannabinoid System on Spontaneous and Induced Contract…
The Effects of JNJ-39393406 on Psychometric Performance and Residual Depressive
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