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arginase-1
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Summary
General Info
Body Atlas
Most Correlated Tissues
Liver
Neutrophil of bone marrow
Fetal liver
Penis
Bone marrow
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Disease Atlas
Most Correlated Diseases
Arginase deficiency
Shock
Nerve injury
Systemic inflammatory response syndrome
Sepsis due to Escherichia coli
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Pharmaco Atlas
Most Correlated Compounds
ursocholic acid
Cetylpyridinium
pristane
zaleplon
Adenylate Cyclase Toxin
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Knockdown Atlas
Most Correlated Gene Perturbations
IL13
LEP
ECI2
MYD88
IQGAP2
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Curated Studies
Most Correlated Studies
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Literature
Most Relevant Literature
Arginase 1 is a key driver of immune suppression in pancreatic cancer.
ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and…
Neutralization of NET-associated human ARG1 enhances cancer immunotherapy.
Arginase 1 and L-arginine coordinate fetal lung development and the initiation of labor in mice.
Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung patholog…
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Clinical Trials
Most Relevant Clinical Trials
A Pilot Study of Recombinant Human Arginase 1 (rhArg1) in Patients With Relapsed or Refractory Leuke…
Pegylated Recombinant Human Arginase 1 in Combination With Oxaliplatin and Capecitabine for the Trea…
Efficacy and Safety of Pegzilarginase in Patients With Arginase 1 Deficiency
Arginase Inhibition in Type 1 and Type 2 Diabetes Mellitus
Efficacy Study of Pegylated Recombinant Human Arginase 1 as a Second-line Therapy in Patients With A…
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