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haemophagocytic lymphohistiocytosis
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General Info
Genetic Markers
Most Correlated Genes
Most Correlated SNPs
FHL3
STX11
FHL1
UNC13D
PRF1
No SNPs found
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Pathway Enrichment
Most Correlated Biogroups
GSE5589_UNSTIM_VS_180MIN_LPS_STIM_MACROPHAGE_DN
leukocyte mediated cytotoxicity
Zinc finger, LIM-type
cell killing
C2 domain
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Curated Studies
Most Correlated Studies
PBMC gene expression in children with active familial hemophagocytic lymphohistiocytosis (FHL)
OMIM - Unspecified immunity deficiency
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Literature
Most Relevant Literature
Fulminant hemophagocytic lymphohistiocytosis secondary to a reactivated EBV infection: a case report…
Hemophagocytic lymphohistiocytosis: an update on diagnosis and pathogenesis.
Salvage therapy of refractory hemophagocytic lymphohistiocytosis with alemtuzumab.
Leishmania in HLH: a rare finding with significant treatment implications.
Haemophagocytic lymphohistiocytosis in a patient with severe burns.
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Clinical Trials
Most Relevant Clinical Trials
A Study to Investigate the Safety and Efficacy of an Anti-IFNγ mAb in Children Affected by Primary H…
Splenectomy as a Treatment for Patient With Relapsed Haemophagocytic Lymphohistiocytosis of Unknown …
Ruxolitinib as First Line Treatment in Primary Haemophagocytic Lymphohistiocytosis (R-HLH)
Study to Assess the Efficacy and Safety of Emapalumab in Primary Haemophagocytic Lymphohistiocytosis
Assessing the Presence of CT-DNA in Lymphoma Associated HLH
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