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hereditary spastic paraplegia
(phenotype)
Summary
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Genetic Markers
Most Correlated Genes
Most Correlated SNPs
SPG21
L1CAM
PHTF2
FEM1A
NRAP
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Pathway Enrichment
Most Correlated Biogroups
GSE33425_CD161_INT_VS_NEG_CD8_TCELL_DN
Maspardin
Alpha/beta hydrolase fold-1
GCM_DENR
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_CIS
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OMIM - Spastic paraplegia
Comparative profiling in 13 muscle disease groups
OMIM - Neuropathy
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Literature
Most Relevant Literature
SPG3A-linked hereditary spastic paraplegia associated with cerebral glucose hypometabolism.
A novel splice site mutation in ERLIN2 causes hereditary spastic paraplegia in a Saudi family.
Construction of wild-type and mutant SPAST vectors for the study of molecular mechanism of hereditar…
Novel SPG11 mutations in Chinese families with hereditary spastic paraplegia with thin corpus callos…
SPAST mutations in Australian patients with hereditary spastic paraplegia.
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Clinical Trials
Most Relevant Clinical Trials
Physiotherapy in Hereditary Spastic Paraplegia
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia
Identification of Modifying Factors in Hereditary Spastic Paraplegia
Effect of Dalfampridine in Patients With Hereditary Spastic Paraplegia
Improving Gait Adaptability in Hereditary Spastic Paraplegia
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