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histone deacetylase inhibitor
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
DHRS2
TXNIP
H1F0
SERPINI1
SYT11
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Pathway Enrichment
Most Correlated Biogroups
heterocyclic compound binding
heterocycle metabolic process
organic cyclic compound metabolic process
organic cyclic compound binding
PUJANA_BRCA1_PCC_NETWORK
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Curated Studies
Most Correlated Studies
Embryonic and trophoblast stem cells treated with Trichostatin A
Pancreatic cell lines treated with chromatin-targeting small molecules
Neurospheres cultured from embryonic striatum and treated with BMP2 or trichostatin A
Pre-cursor B cell acute lymphoblastic leukemia cells and patient samples treated with vorinostat
CD4-positive T cells from healthy donors treated with suberoylanilide hydroxamic acid
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Literature
Most Relevant Literature
Histone deacetylase (HDACs) inhibitors: Clinical applications.
An updated patent review of histone deacetylase (HDAC) inhibitors in cancer (2020 - present).
Underlying anti-cancer mechanisms of histone deacetylase (HDAC) inhibitors in tamoxifen-resistant br…
NO-HDAC dual inhibitors.
The impact of selective HDAC inhibitors on the transcriptome of early mouse embryos.
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Clinical Trials
Most Relevant Clinical Trials
Safety and Efficacy of Quisinostat, a Histone Deacetylase Inhibitor, in Combination With Chemotherap…
Dietary Histone Deacetylase Inhibitors (HDAC)
Safety Study of the Histone Deacetylase Inhibitor, CHR-3996, in Patients With Advanced Solid Tumours
Anti-PD-1 Antibody Combined With Histone Deacetylase Inhibitor in Patients With Advanced Cervical Ca…
Selective Estrogen Receptor Modulators to Enhance the Efficacy of Viral Reactivation With Histone De…
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