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QuickView for natalizumab (compound)


Genetic Markers

Most Correlated Genes

  1. ITGA4
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Pathway Enrichment

Most Correlated Biogroups

  1. clathrin-dependent extracellular exosome endocytosis
  2. positive regulation of leukocyte tethering or rolling
  3. positive regulation of leukocyte adhesion to vascular endothelial cell
  4. protein antigen binding
  5. VANLOO_SP3_TARGETS_UP
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Curated Studies

Most Correlated Studies

  1. Multiple sclerosis patients in remission and relapse
  2. CD4+ T cells stimulated and then restimulated in the presence or absence of natalizumab
  3. CD4+ T cells of seasonal allergic rhinitis and multiple sclerosis patients response to NZB or GC
  4. Drug target sets for approved compounds
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Literature

Most Relevant Literature

  1. Intravenous or subcutaneous natalizumab in patients with relapsing-remitting multiple sclerosis: inv…
  2. Natalizumab for GVHD: too little or too late?
  3. Brain volume increase after discontinuing natalizumab therapy: Evidence for reversible pseudoatrophy…
  4. Natalizumab extended interval dosing: what about wearing-off effect?
  5. Peptide Mimotope-Enabled Quantification of Natalizumab Arm Exchange During Multiple Sclerosis Treatm…
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Clinical Trials

Most Relevant Clinical Trials

  1. Natalizumab Re-Initiation of Dosing
  2. Natalizumab and Chronic Inflammation
  3. Natalizumab Temporary Discontinuation Study
  4. Open-Label Natalizumab Safety Extension Study
  5. Natalizumab Subcutaneous Immunogenicity and Safety Study
Explore Clinical Trials Results
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