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QuickView for nicotinic cholinergic agonist (compound)


Genetic Markers

Most Correlated Genes

  1. CHRNA2
  2. MMP7
  3. AFF1
  4. KCNB1
  5. NUCKS1
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Pathway Enrichment

Most Correlated Biogroups

  1. heterocyclic compound binding
  2. organic cyclic compound binding
  3. PUJANA_BRCA1_PCC_NETWORK
  4. DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP
  5. KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP
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Curated Studies

Most Correlated Studies

  1. Effects of nicotine on the palate development
  2. Oral keratinocytes treated with ethanol and nicotine
  3. Prostate cancer cell lines treated with nicotine
  4. Prostate of TRAMP mice exposed to nicotine
  5. Liver, breast and endometrial cell lines exposed to 34 toxicological compounds
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Literature

Most Relevant Literature

  1. The antinociceptive effects of nicotinic partial agonists varenicline and sazetidine-A in murine acu…
  2. Analgesic effects mediated by neuronal nicotinic acetylcholine receptor agonists: correlation with d…
  3. Partial agonists for α4β2 nicotinic receptors stimulate dopaminergic neuron firing with relatively e…
  4. A fluorinated quinuclidine benzamide named LMA 10203 acts as an agonist of insect nicotinic acetylch…
  5. The nicotinic α7 receptor agonist GTS-21 improves cognitive performance in ketamine impaired rhesus …
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Clinical Trials

Most Relevant Clinical Trials

  1. Phase 2 Trial of a Nicotinic Agonist in Schizophrenia
  2. Nicotine Effects on Endophenotypes of Schizophrenia
  3. Depressed Mood Improvement Through Nicotine Dosing 2
  4. Depressed Mood Improvement Through Nicotine Dosing 3
  5. Nicotinic Cholinergic Modulation as a Novel Treatment Strategy for Aggression Associated With Autism
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