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nuclear export
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NextBio Summary
General Info
Body Atlas
Most Correlated Tissues
Thymus gland
Kidney
Endometrium
Peritoneum
Pons
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Disease Atlas
Most Correlated Diseases
Shock
Listeriosis
Contact dermatitis
Hemorrhagic shock
Disease due to Orthopoxvirus
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Pharmaco Atlas
Most Correlated Compounds
enterotoxin F, Staphylococcal
CGP 60474
flavopiridol
AT 7519
dinaciclib
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Knockdown Atlas
Most Correlated Gene Perturbations
TLK2
EBNA1BP2
FUBP3
COL7A1
AURKB
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Curated Studies
Most Correlated Studies
Neural development of iPSCs derived from Autistic patients with BCKD-kinase mutations
Expression profile of HDAC treated LNCaP cells
Induced pluripotent stem cells derived from fibroblasts of Down's syndrome patients
GSK cancer cell line transcript profiling
B cell and PBMC co-cultures stimulated with anti-IgM and superantigens
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Literature
Most Relevant Literature
Targeting XPO1-Dependent Nuclear Export in Cancer.
PCID2 assists in the nuclear export of nucleophosmin (NPM) in HeLa cells.
PCID2, a subunit of the Drosophila TREX-2 nuclear export complex, is essential for both mRNA nuclear…
Nuclear export restricts Gdown1 to a mitotic function.
Genetic profiling of protein burden and nuclear export overload.
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Clinical Trials
Most Relevant Clinical Trials
A Study to Evaluate Dual mTORC1/2 Inhibitor (ATG 008) or Selective Inhibitor of Nuclear Export Compo…
Phase I Trial of the Selective Inhibitor of Nuclear Export, KPT-330, in Relapsed Childhood ALL and A…
Selective Inhibitor of Nuclear Export, Selinexor (KPT-330) in Combination With Paclitaxel and Carbop…
Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330) in Patients With Myelodysplastic Sy…
Safety Study of the Selective Inhibitor of Nuclear Export (SINE) KPT-330 in Patients With Advanced H…
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