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pre-B cell receptor
(compound)
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Genetic Markers
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Pathway Enrichment
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Curated Studies
Most Correlated Studies
Pre-B cells overexpressing BCR-ABL1 and lacking pre-B cell receptor (IGHM)
Large pre-B cells positive for CD19, CD43 and BP1 in Ikaros dominant negative mice
Pre-B BH1 cells with inducible expression of Ikaros and IL-7 withdrawal
Pre-B cells bone marrow derived IL-7 stimulated and activated with anti-IgM
B cells and stromal cells participate in complex interactions and communicate during development
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Literature
Most Relevant Literature
Science Signaling Podcast for 29 November 2016: Pre-B cell receptor signaling in leukemia.
Dynamic pre-BCR homodimers fine-tune autonomous survival signals in B cell precursor acute lymphobla…
Pre-B cell receptor binding to galectin-1 modifies galectin-1/carbohydrate affinity to modulate spec…
The pre-B-cell receptor checkpoint in acute lymphoblastic leukaemia.
Niche-expressed Galectin-1 is involved in pre-B acute lymphoblastic leukemia relapse through pre-B c…
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Clinical Trials
Most Relevant Clinical Trials
Immunity to Hepatitis B Vaccine
Anti-CD19:TCRζ Chimeric Antigen Receptor-T Cells in the Treatment for CD19+ B Cell Lymphoma
CAR20.19.22 T-cells in Relapsed, Refractory B-cell Malignancies
ENABLE (Engaging Toll-like Receptor Signalling for B-cell Lymphoma Chimeric Antigen Receptor Therapy…
ET190L1-ARTEMIS™ T Cells in Relapsed, Refractory B Cell Leukemia and Lymphoma
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