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(e.g. Bleomycin, rs7903146, FOXP1, T cell receptor signaling pathway, HIV infection, Retina)
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QuickView for second-generation antihistamines (compound)


Genetic Markers

Most Correlated Genes

  1. SULT1A1
  2. UGT2B4
  3. HRH1
  4. CYP3A4
  5. CALML4
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Pathway Enrichment

Most Correlated Biogroups

  1. regulation of nitrogen compound metabolic process
  2. organic cyclic compound metabolic process
  3. response to organic substance
  4. heterocycle metabolic process
  5. cellular aromatic compound metabolic process
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Curated Studies

Most Correlated Studies

  1. Cerebrocortical cells treated with blood-brain barrier penetrant clinic-tested drugs
  2. Hearts of rats exposed variety of toxicants
  3. Drug Matrix In Vitro Toxicogenomic Study - Rat Hepatocytes [Codelink]
  4. Drug target sets for approved compounds
  5. Broad Connectivity Map (CMAP 2.0) compound database
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Literature

Most Relevant Literature

  1. Investigating the use of liquisolid compacts technique to minimize the influence of pH variations on…
  2. Molecularly imprinted nano particles combined with miniaturized homogenous liquid-liquid extraction …
  3. Thermally triggered mucoadhesive in situ gel of loratadine: β-cyclodextrin complex for nasal deliver…
  4. Synthesis and biological evaluation of cyanoguanidine derivatives of loratadine.
  5. Evaluation of efficacy and safety of loratadine in the treatment of childhood asthma].
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Clinical Trials

Most Relevant Clinical Trials

  1. Effects of Second-generation Antihistamine Bepotastine on Cough Outcomes in Cough Patients With Alle…
  2. A Safety and Efficacy Study of Remibrutinib in the Treatment of CSU in Japanese Adults Inadequately …
  3. This Was a Dose-finding Study to Evaluate Efficacy and Safety of LOU064 in Patients With CSU Inadequ…
  4. A Phase 3 Study of Efficacy and Safety of Remibrutinib in the Treatment of CSU in Adults Inadequatel…
  5. A Phase 3 Study of Efficacy and Safety of Remibrutinib in the Treatment of CSU in Adults Inadequatel…
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