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sphingosine
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Summary
General Info
Genetic Markers
Most Correlated Genes
PDK4
FOS
EGR2
HSPA1B
EGR1
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Pathway Enrichment
Most Correlated Biogroups
HALLMARK_TNFA_SIGNALING_VIA_NFKB
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
NAGASHIMA_NRG1_SIGNALING_UP
regulation of nitrogen compound metabolic process
WONG_ADULT_TISSUE_STEM_MODULE
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Curated Studies
Most Correlated Studies
Expression data from human Jurkat T cells exposed to 31 compounds
Acute myeloblastic leukemia Kasumi-1 cells treated with sphingosine analogue FTY720
Fibrotic and immune pathway signatures in dermal fibroblasts
Breast cancer MCF7 cells treated with sphingosine-1-phosphate, FTY720 or SAHA
Cerebrocortical cells treated with blood-brain barrier penetrant clinic-tested drugs
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Literature
Most Relevant Literature
Regulation of the sphingosine kinase/sphingosine 1-phosphate pathway.
Topical treatment targeting sphingosine-1-phosphate and sphingosine lyase abrogates experimental all…
The Sphingosine-1-phospate receptor 1 mediates S1P action during cardiac development.
Sphingosine pathway deregulation in endometriotic tissues.
H-Ras increases release of sphingosine resulting in down-regulation of TSP-1 in non-transformed cell…
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Clinical Trials
Most Relevant Clinical Trials
Evaluation of Plasma Sphingosine-1-Phosphate as A Diagnostic and Prognostic Biomarkers of Community-…
A Study to Assess the Relative Bioavailability of Different Formulations of GSK2018682, a Sphingosin…
Predicting Disease Activity and Rebound Risk in MS Patients Treated With Sphingosine-1-phosphate Rec…
Opaganib, a Sphingosine Kinase-2 (SK2) Inhibitor in COVID-19 Pneumonia
Activation of the Sphingosine-1-phosphate (S1P) to S1P1 Receptor Subtype (S1PR1) Axis in Patients Wi…
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