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tubulin modulators
(compound)
Summary
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Genetic Markers
Most Correlated Genes
ALAS2
ATF3
GDF15
TUBB4B
CCL2
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Pathway Enrichment
Most Correlated Biogroups
DODD_NASOPHARYNGEAL_CARCINOMA_DN
PILON_KLF1_TARGETS_DN
FISCHER_DREAM_TARGETS
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP
PUJANA_BRCA1_PCC_NETWORK
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Curated Studies
Most Correlated Studies
Breast tumors with pathologic complete response (pCR) or residual disease (RD) upon chemotherapy
Radioresistant cell lines exposed to single dose alpha particle and gamma ray exposure
OV90 sublines selected for resistance to cisplatin, doxorubicin and paclitaxel
Ovarian tumor biopsies from a Phase I dasatinib trial
Etoposide-treated HEK293 cells expressing p65 wt or p65 S547A non-phosphorylable mutant
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Literature
Most Relevant Literature
Identification of novel αβ-tubulin modulators with antiproliferative activity directed to cancer the…
Morphological profiling by means of the Cell Painting assay enables identification of tubulin-target…
Potential colchicine binding site inhibitors unraveled by virtual screening, molecular dynamics and …
Imidazoles and benzimidazoles as tubulin-modulators for anti-cancer therapy.
Comprehensive Analysis of Binding Sites in Tubulin.
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Clinical Trials
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To Study the Effects of Addition of Mebendazole to Lenvatinib in Cirrhotics With Advanced Hepatocell…
Epithelial Mesenchymal Transition and Periodontitis
PLatelets Acetyl-CoA Carboxylase Phosphorylation State in SEPtic Shock
Fetal Alcohol Spectrum Disorder-Is This a Ciliopathy?
Colchicine/Statins for the Prevention of COVID-19 Complications (COLSTAT) Trial
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