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QuickView for ALK5 (gene)
Most Relevant Literature
- Advances in the discovery of activin receptor-like kinase 5 (ALK5) inhibitors.
- The endometrial cancer A230V-ALK5 (TGFBR1) mutant attenuates TGF-β signaling and exhibits reduced in…
- Identification of TGFBR1 Gene Variants in Two Chinese Pedigrees with Loeys-Dietz Syndrome.
- Generation of two induced pluripotent stem cell lines from Loeys-Dietz syndrome patients carrying he…
- NPC1 controls TGFBR1 stability in a cholesterol transport-independent manner and promotes hepatocell…
Most Relevant Clinical Trials
- First in Human Dose Escalation Study of Vactosertib (TEW-7197) in Subjects With Advanced Stage Solid…
- Vactosertib and Durvalumab in Gastric Cancer
- First in Human Dose Escalation Study of YL-13027 in Subjects With Advanced Stage Solid Tumors
- TD-1058 First-In-Human Study in Healthy Subjects and Subjects With Idiopathic Pulmonary Fibrosis
- Vactosertib in Combination w/ Pomalidomide in Relapsed or Relapsed and Refractory Multiple Myeloma
