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QuickView for ASXL1 (gene)


Body Atlas

Most Correlated Tissues

  1. T Lymphocyte (regulatory) of peripheral blood
  2. Natural killer cell of peripheral blood
  3. Fetal brain
  4. Fetal lung
  5. T Lymphocyte (CD4+) of peripheral blood
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Disease Atlas

Most Correlated Diseases

  1. Sarcoidosis
  2. T-cell lymphoma
  3. Pyloric ulcer
  4. Drug resistance
  5. Liver transplant disorder
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Pharmaco Atlas

Most Correlated Compounds

  1. benz(a)anthracene
  2. styrene oxide
  3. Fenretinide
  4. Harmaline
  5. Penicillin G Benzathine
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. SSBP4
  2. FNIP1
  3. KLHL6
  4. SBDS
  5. NCL
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Targeting BIRC5 as a therapeutic approach to overcome ASXL1-associated decitabine resistance.
  2. Asxl1 deletion disrupts MYC and RNA polymerase II function in granulocyte progenitors.
  3. ASXL1/2 mutations and myeloid malignancies.
  4. CHIP-associated mutant ASXL1 in blood cells promotes solid tumor progression.
  5. The ASXL1-G643W variant accelerates the development of CEBPA mutant acute myeloid leukemia.
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Clinical Trials

Most Relevant Clinical Trials

  1. Clonal Architecture of ASXL1-mutated Myelofibrosis
  2. ASXL-Related Disorders Registry
  3. Busulfan, Fludarabine, Donor Stem Cell Transplant, and Cyclophosphamide in Treating Patients With Mu…
  4. Studying Tissue and Blood Samples From Patients With Acute Myeloid Leukemia
  5. Clonal Hematopoiesis of Indeterminate Potential in Venous Thromboembolism
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