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Cdk9
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Summary
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Body Atlas
Most Correlated Tissues
Thymus gland
Cerebellar vermis
Pituitary gland
Colon mucosa
Ileum mucosa
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Disease Atlas
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Knockdown Atlas
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Curated Studies
Most Correlated Studies
D. melanogaster DL1 cells depleted of Cdk9 and infected with VSV
Colon cancer cells (HCT116) with CDK9, CDK12 or CDK13 knockdown
L1000 CMAP Prostate cancer PC3 cells with gene overexpression perturbations (1 of 2)
L1000 CMAP Prostate cancer VCaP cells with gene overexpression perturbations
L1000 CMAP Colorectal cancer HT 29 cells with gene overexpression perturbations
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Literature
Most Relevant Literature
Potent inhibitors targeting cyclin-dependent kinase 9 discovered via virtual high-throughput screeni…
Selective inhibition of CDK9 in triple negative breast cancer.
Identification of a Novel Selective CDK9 Inhibitor for the Treatment of CRC: Design, Synthesis, and …
RNF20 contributes to epigenetic immunosuppression through CDK9-dependent LSD1 stabilization.
Sevoflurane-induced P300 promotes neuron apoptosis via Sp1/CDK9 pathway.
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Clinical Trials
Most Relevant Clinical Trials
A Study of PRT2527 in Participants With Advanced Solid Tumors
Efficacy Study Of P276-00 In Subjects Of Malignant Melanoma Positive For Cyclin D1 Expression
A Study of PRT2527 in Participants With Relapsed/Refractory Hematologic Malignancies
A Clinical Trial Comparing Gemcitabine and Carboplatin With and Without P276-00 in Subjects With Met…
A Study of GFH009 in Patients With Hematologic Malignancies
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