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Exportin 1
(compound)
Summary
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Genetic Markers
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Curated Studies
Most Correlated Studies
Mouse embryonic fibroblasts (MEFs) depleted of Exportin-5
Fibroblast IMR90 cells with ER-RAS G12V overexpression and XPO7 shRNA knockdown
Oral epithelial cells from gingiva with TNFa induced inflammation treated with resolvin D1
Glioblastoma A172 cells with ADAR1 and STAU1 siRNA knockdown
Lung cancer A549 cells infected for 1hr with respiratory syncytial virus strain A2
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Literature
Most Relevant Literature
Safety of selinexor as the only exportin 1 (XPO1) inhibitor so far: a post-marketing study based on …
Exportin 1-mediated nuclear/cytoplasmic trafficking controls drug sensitivity of classical Hodgkin's…
C646 degrades Exportin-1 to modulate p300 chromatin occupancy and function.
Differential impact of exportin-1-mediated nuclear export of RNAs on the RNA content of extracellula…
Exportin 1 governs the immunosuppressive functions of myeloid-derived suppressor cells in tumors thr…
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Clinical Trials
Most Relevant Clinical Trials
A Phase 1 Trial of a Novel XPO1 Inhibitor in Patients With Advanced Solid Tumors
Selinexor in Treating Patients With Abiraterone Acetate and/or Enzalutamide Refractory Metastatic Ca…
Single Patient Use of Selinexor and Dexamethasone for a Patient With Multiple Myeloma
Pre-approval Access Single Patient Request for Teclistamab (JNJ-64007957)
Elotuzumab, Selinexor, and Dexamethasone for Relapsed Refractory Multiple Myeloma
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