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Fragile X
Summary
General Info
Curated Studies
Most Correlated Studies
OMIM - Congenital disorder
Induced pluripotent stem cell expression patterns compared to parental cells and stem cells
The 3UTR of FMR1 mRNA is a target of miR101, miR129-5p and miR-221
Induced pluripotent stem (iPS) cells derived from fibroblasts of fragile X syndrome patients
Frontal cortex tissue of brains of fragile X syndrome patients
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Most Relevant Literature
Genetic Deletion of FXR1 Reduces Intimal Hyperplasia and Induces Senescence in Vascular Smooth Muscl…
LLPS of FXR1 drives spermiogenesis by activating translation of stored mRNAs.
FXR1 splicing is important for muscle development and biomolecular condensates in muscle cells.
Fxr1 regulates sleep and synaptic homeostasis.
RNA-binding protein FXR1 is presented in rat brain in amyloid form.
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Clinical Trials
Most Relevant Clinical Trials
Riluzole in Fragile X Syndrome
Novel Clinical Target in Fragile X Syndrome
Neuroimaging GABA Physiology in Fragile X Syndrome
Validation of Saliva in the Esoterix Genetic Laboratories Fragile X Assay
Protein Synthesis in the Brain of Patients With Fragile X Syndrome
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