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Guanabenz
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Summary
General Info
Genetic Markers
Most Correlated Genes
ADRA2A
S100A8
ANP32A
CTSS
SHCBP1
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Pathway Enrichment
Most Correlated Biogroups
GSE17721_CPG_VS_GARDIQUIMOD_12H_BMDC_UP
MODULE_146
GSE18281_CORTICAL_THYMOCYTE_VS_WHOLE_CORTEX_THYMUS_UP
ZHU_CMV_ALL_DN
HAMAI_APOPTOSIS_VIA_TRAIL_UP
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Curated Studies
Most Correlated Studies
Multiple myeloma RPMI8226 cells treated with eIF2a phosphatase inhibitors, Guanabenz and Sal003
Drug target sets for approved compounds
Broad Connectivity Map (CMAP 2.0) compound database
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
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Literature
Most Relevant Literature
Evaluation of the effect of guanabenz-loaded nanoparticles on chronic toxoplasmosis in mice.
Guanabenz-an old drug with a potential to decrease obesity.
Guanabenz ameliorates disease in vanishing white matter mice in contrast to sephin1.
Geometric Isomer of Guanabenz Confers Hepatoprotection to a Murine Model of Acetaminophen Toxicity.
Rebound of cyst number following discontinuation of guanabenz treatment for latent toxoplasmosis.
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Clinical Trials
Most Relevant Clinical Trials
Oral Guanabenz for Multiple Sclerosis
Study Evaluating the Biologic Activity of Guanabenz in Bone Metastasis
Efficacy and Safety of Guanabenz for Nonalcoholic Fatty Liver Disease
Longitudinal Investigation of I2BS in PD
A Study to Assess the Safety, Tolerability and Efficacy of IONIS-AGT-LRx, an Antisense Inhibitor Adm…
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