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H3 3
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Curated Studies
Most Correlated Studies
Mutations in histone H3.3 in pediatric glioblastoma
Mesenchymal progenitor cells expressing histone H3.3 (H3F3A) K36M mutation
Neurons and astrocytes with manipulated H3.1/H3.3 gene expression and KCl stimulation
Neural progenitor cells modeling of pediatric gliomas by K27M mutation in histone H3.3 variant
High-grade gliomas with histone H3.3 and TP53 mutations and high levels of PDGFRA
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Literature
Most Relevant Literature
HIRA vs. DAXX: the two axes shaping the histone H3.3 landscape.
Histone Variant H3.3 Controls Arabidopsis Fertility by Regulating Male Gamete Development.
The Histone Variant H3.3 Is Required for Plant Growth and Fertility in Arabidopsis.
Knockout tales: the versatile roles of histone H3.3 in development and disease.
Multilevel interrogation of H3.3 reveals a primordial role in transcription regulation.
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Clinical Trials
Most Relevant Clinical Trials
Neoantigen Vaccine Therapy Against H3.3-K27M Diffuse Intrinsic Pontine Glioma
Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors
H3: Healthy Minds, Healthy Children, Healthy Chicago Project Evaluation
Pilot Study of B7-H3 CAR-T in Treating Patients With Recurrent and Refractory Glioblastoma
A MultIceNTER Phase I Peptide VaCcine Trial for the Treatment of H3-Mutated Gliomas
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