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QuickView for HCK (gene)


Body Atlas

Most Correlated Tissues

  1. Neutrophil of bone marrow
  2. Whole blood
  3. Leukocyte (polymorphonuclear) of peripheral blood
  4. Mononuclear cell of peripheral blood
  5. Myeloid cells of peripheral blood
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Disease Atlas

Most Correlated Diseases

  1. Vasculitis
  2. Poisoning by drug AND/OR medicinal substance
  3. Disease caused by parasite
  4. Sepsis due to coagulase negative Staphylococcus
  5. Coliform mastitis
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Pharmaco Atlas

Most Correlated Compounds

  1. ibufenac
  2. Neupogen
  3. Stem Cell Factor
  4. Harmine
  5. ubiquinol
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. SMIM26
  2. C2CD2
  3. TADA3
  4. IGH
  5. RBPMS
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. HCK induces macrophage activation to promote renal inflammation and fibrosis via suppression of auto…
  2. Inhibition of HCK in myeloid cells restricts pancreatic tumor growth and metastasis.
  3. Inhibition of the SRC Kinase HCK Impairs STAT3-Dependent Gastric Tumor Growth in Mice.
  4. Expression of a Constitutively Active Form of Hck in Chondrocytes Activates Wnt and Hedgehog Signali…
  5. Genomic Analysis of Kidney Allograft Injury Identifies Hematopoietic Cell Kinase as a Key Driver of …
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Clinical Trials

Most Relevant Clinical Trials

  1. Study of Bone Marrow Samples From Patients With Acute Leukemia
  2. A Phase II Study of Dasatinib in the Treatment of Relapsed or Plateau Phase Multiple Myeloma
  3. Oral STAT3 Inhibitor, TTI-101, in Patients With Advanced Cancers
  4. Dasatinib in Treating Patients With Previously Treated Metastatic Colorectal Cancer
  5. Ibrutinib in Treating Patients With Refractory Metastatic Cutaneous Melanoma
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