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HIF 1alpha
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General Info
Curated Studies
Most Correlated Studies
Hepatocellular carcinoma HepG2 cells grown as spheroids and depleted of HIF-1alpha or HIF-2alpha
Differential Gene Up-regulation by HIF-1a and HIF-2a in HEK293T
Hepatocytes with conditional HIF-1a knockout, cultured in hypoxia
Liver from mice with constitutively active HIF-1a and HIF-2a or VHL KO
HIF-1α and HIF-2α knockdown in MCF-7 breast cancer cell line under hypoxic conditions
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Literature
Most Relevant Literature
Engineering nanomedicines to inhibit hypoxia-inducible Factor-1 for cancer therapy.
HIF-1α is transcriptionally regulated by NF-κB in acute kidney injury.
An order-to-disorder structural switch regulates HIF-1 transcription through S247 phosphorylation in…
The evolutionarily conserved hif-1/bnip3 pathway promotes mitophagy and mitochondrial fission in cru…
One-pot synthesis of a microporous organosilica-coated cisplatin nanoplatform for HIF-1-targeted com…
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Clinical Trials
Most Relevant Clinical Trials
Effect of Dutasteride on HIF-1alpha and VEGF in the Prostate
A Pilot Study of EZN-2968, an Antisense Oligonucleotide Inhibitor of HIF-1alpha, in Adults With Adva…
A Pilot Trial of Oral Topotecan for the Treatment of Refractory Advanced Solid Neoplasms Expressing …
Human Liver Explants for HIF-1 Alpha Analysis/Comparison (HIF HCC)
Safety and Efficacy Study of Ad2/Hypoxia Inducible Factor (HIF)-1α/VP16 Gene Transfer in Patients Wi…
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