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QuickView for HRAS protein
Most Correlated Studies
- Skin fibroblasts from HGPS patients - TERT immortalized or TERT HRAS SV40 T transformed
- Treated keratinocyte HaCaT cell line overexpressing EGFR, RELA (p65), or HRAS-VAL12D
- Ras driven tumors in mouse mammary glands and non-transformed NMuMG line treated w/TGFβ
- Mammary tumors from 8 different mouse models of human breast cancer
- Response to TNF-alpha in melanoma cell lines with different mutations
Most Relevant Literature
- Identification of an H-Ras nanocluster disrupting peptide.
- Capturing RAS oligomerization on a membrane.
- Structural insights into isoform-specific RAS-PI3Kα interactions and the role of RAS in PI3Kα activa…
- Dependence of NPPS creates a targetable vulnerability in RAS-mutant cancers.
- GTP-Bound N-Ras Conformational States and Substates Are Modulated by Membrane and Point Mutation.
Most Relevant Clinical Trials
- Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS …
- Glycemic and Appetite Effects of a Pre-meal Whey-Protein Microgel
- A High-PRotein Mediterranean Diet and Resistance Exercise for Cardiac Rehabilitation: a Pilot Random…
- Study of DCC-3084 in Participants With Advanced Malignancies Driven by the Mitogen-Activated Protein…
- Combination Trial of Tipifarnib and Alpelisib in Adult Recurrent/ Metastatic Head and Neck Squamous …
