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IRF 4
Summary
General Info
Curated Studies
Most Correlated Studies
Stimulated B cells with induced IRF4 expression after IRF4 knockout
Primary macrophages infected with HIV-1 or control for 2,4, or 7d
Bone marrow-derived macrophages from Irf4 deficient or heterozygous mice cultured with IL-4
Granulocyte-monocyte progenitor expression profiles from IR4 and IRF8 deficient mice
Gene expression under different levels of IL-7 & after rescue of genetic defect
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Literature
Most Relevant Literature
Human inborn errors of immunity associated with IRF4.
Transcriptional reprogramming by mutated IRF4 in lymphoma.
A neomorphic mutation in the interferon activation domain of IRF4 causes a dominant primary immunode…
Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human aut…
IRF4 induces M1 macrophage polarization and aggravates ulcerative colitis progression by the Bcl6-de…
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Clinical Trials
Most Relevant Clinical Trials
Multi-Organ Denervation With the iRF System to RedUce Sympathetic Drive
Study of Safety and Efficacy of Brolucizumab 6 mg Dosed Every 4 Weeks Compared to Aflibercept 2 mg D…
Evaluation of the Integrated Radio Frequency Denervation System for the Treatment of Hypertension
JOINTS Study - Joint Replacement Outcome in Inpatient Rehabilitation Facilities and Nursing Treatmen…
Zidovudine, Interferon Alfa-2b, PEG-Interferon Alfa-2b in Patients With HTLV-I Associated Adult T-Ce…
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