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Loxapine
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
CYP51A1
HMGCS1
DDX27
ALOX15
PPP2CA
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Pathway Enrichment
Most Correlated Biogroups
response to organic substance
regulation of phosphorus metabolic process
PILON_KLF1_TARGETS_DN
positive regulation of protein metabolic process
regulation of nitrogen compound metabolic process
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Curated Studies
Most Correlated Studies
Cerebrocortical cells treated with blood-brain barrier penetrant clinic-tested drugs
Drug target sets for approved compounds
Broad Connectivity Map (CMAP 2.0) compound database
Liver Pharmacology and Xenobiotic Response Repertoire
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
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Literature
Most Relevant Literature
Loxapine P-glycoprotein interactions in vitro.
Inhaled loxapine: a new treatment for agitation in schizophrenia or bipolar disorder.
Now take a deep breath: inhaled loxapine for the treatment of acute agitation.
In vitro aerosol characterization of Staccato(®) Loxapine.
Combination loxapine and aripiprazole for refractory hallucinations in schizophrenia.
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Clinical Trials
Most Relevant Clinical Trials
Staccato Loxapine Single Dose PK
A Study of Staccato Loxapine (ADASUVE®) for Inhalation
Staccato Loxapine in Migraine (in Clinic)
Staccato Loxapine Multidose PK
Loxapine in the Management of Restlessness During Mechanical Ventilation Weaning
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