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MDM2
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NextBio Summary
General Info
Body Atlas
Most Correlated Tissues
Breast tissue
Placenta
Pancreas
Thymus gland
Fallopian tube
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Disease Atlas
Most Correlated Diseases
Congenital glucose-galactose malabsorption
Multiple organ failure
Hemorrhagic shock
Radiation injury
Rhinitis
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Pharmaco Atlas
Most Correlated Compounds
perfosfamide
Ethyl Methanesulfonate
PHA 739358
mitomycin C-dextran
phenethicillin
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Knockdown Atlas
Most Correlated Gene Perturbations
PCSK9
NELFB
XRN2
OLR1
BCKDK
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Curated Studies
Most Correlated Studies
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Literature
Most Relevant Literature
Dysfunction of the MDM2/p53 axis is linked to premature aging.
Splice variants of MDM2 in oncogenesis.
Non-linear feedback control of the p53 protein-mdm2 inhibitor system using the derivative-free non-l…
MDM2 prevents spontaneous tubular epithelial cell death and acute kidney injury.
MDM2 beyond cancer: podoptosis, development, inflammation, and tissue regeneration.
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Clinical Trials
Most Relevant Clinical Trials
MDM2 Inhibitor AMG-232 (KRT-232) and Radiation Therapy in Treating Patients With Soft Tissue Sarcoma
Phase 1 Study of the Dual MDM2/MDMX Inhibitor ALRN-6924 in Pediatric Cancer
Ascending Dose and Exploratory Expansion Study of DS-3032b, an Oral MDM2 Inhibitor, in Subjects With…
This Study Evaluates KRT-232, a Novel Oral Small Molecule Inhibitor of MDM2, for the Treatment of Pa…
A Study of the Safety and Pharmacokinetics of RO6839921, An MDM2 Antagonist, in Patients With Advanc…
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