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QuickView for MDM2 (gene)


Body Atlas

Most Correlated Tissues

  1. Breast tissue
  2. Placenta
  3. Pancreas
  4. Thymus gland
  5. Fallopian tube
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Disease Atlas

Most Correlated Diseases

  1. Congenital glucose-galactose malabsorption
  2. Multiple organ failure
  3. Hemorrhagic shock
  4. Radiation injury
  5. Rhinitis
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Pharmaco Atlas

Most Correlated Compounds

  1. perfosfamide
  2. Ethyl Methanesulfonate
  3. PHA 739358
  4. mitomycin C-dextran
  5. phenethicillin
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. PCSK9
  2. NELFB
  3. XRN2
  4. OLR1
  5. BCKDK
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. mdm2 oncogene in laryngeal squamous cell carcinoma.
  2. Guardian of genome on the tract: Wild type p53-mdm2 complex inhibition in healing the breast cancer.
  3. Splicing factor DHX15 affects tp53 and mdm2 expression via alternate splicing and promoter usage.
  4. Dysfunction of the MDM2/p53 axis is linked to premature aging.
  5. Splice variants of MDM2 in oncogenesis.
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Clinical Trials

Most Relevant Clinical Trials

  1. MDM2 Inhibitor AMG-232 (KRT-232) and Radiation Therapy in Treating Patients With Soft Tissue Sarcoma
  2. Phase 1 Study of the Dual MDM2/MDMX Inhibitor ALRN-6924 in Pediatric Cancer
  3. Ascending Dose and Exploratory Expansion Study of DS-3032b, an Oral MDM2 Inhibitor, in Subjects With…
  4. This Study Evaluates KRT-232, a Novel Oral Small Molecule Inhibitor of MDM2, for the Treatment of Pa…
  5. A Study of the Safety and Pharmacokinetics of RO6839921, An MDM2 Antagonist, in Patients With Advanc…
Explore Clinical Trials Results
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