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QuickView for MDM2 proteins
Most Correlated Studies
- Breast adenocarcinoma cells treated with nutlin-3a or/and Wip1 inhibitor GSK2830371
- Hepatocyte cells of Wistar rats treated with 29 different hepatotoxic compounds
- Acute monocytic leukemia MOLM-13 cells treated with the stapled peptide ALRN-6924
- Neuroblastoma SHEP cells with dox-induced/uninduced MYCN before or after nutlin-3a treatment
- p53-reactivating drug RITA treated HCT116 wildtype and TP53 null cells
Most Relevant Literature
- Discovery of ganoderic acid A (GAA) PROTACs as MDM2 protein degraders for the treatment of breast ca…
- Transfected SARS-CoV-2 spike DNA for mammalian cell expression inhibits p53 activation of p21(WAF1),…
- Death-associated protein kinase 1 phosphorylates MDM2 and inhibits its protein stability and functio…
- Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Inter…
- Induction of the Mdm2 gene and protein by kinase signaling pathways is repressed by the pVHL tumor s…
Most Relevant Clinical Trials
- Phase 1 Study of the Dual MDM2/MDMX Inhibitor ALRN-6924 in Pediatric Cancer
- Ascending Dose and Exploratory Expansion Study of DS-3032b, an Oral MDM2 Inhibitor, in Subjects With…
- Testing the Addition of KRT-232 (AMG 232) to Usual Chemotherapy for Relapsed Multiple Myeloma
- KRT-232 (AMG-232) and Decitabine in Treating Patients With Relapsed, Refractory, or Newly-Diagnosed …
- A Phase Ib Study of APG-115 Single Agent or in Combination With Azacitidine or Cytarabine in Patient…
