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QuickView for MGMT (gene)


Body Atlas

Most Correlated Tissues

  1. Liver
  2. Parotid gland
  3. Granulocyte-macrophage progenitor cell of bone marrow
  4. Fallopian tube
  5. Sigmoid colon
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Disease Atlas

Most Correlated Diseases

  1. Irritable bowel syndrome
  2. Drug resistance to insulin
  3. Anomaly of chromosome pair 7
  4. Drug resistance
  5. Intestinal infectious disease
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Pharmaco Atlas

Most Correlated Compounds

  1. Angiotensins
  2. N-((3S)-1-azabicyclo(2.2.2)oct-3-yl)-1H-indazole-3-carboxamide hydrochloride
  3. Aflatoxins
  4. PGF protein, human
  5. Aflatoxin B1
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. FNDC5
  2. UNC93B1
  3. EXOC5
  4. PPARD
  5. TPM3
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Association between MGMT Enhancer Methylation and MGMT Promoter Methylation, MGMT Protein Expression…
  2. MGMT in TMZ-based glioma therapy: Multifaceted insights and clinical trial perspectives.
  3. MGMT protein expression is a reliable predictive biomarker for temozolomide-containing chemotherapy …
  4. A systematic review of high impact CpG sites and regions for MGMT methylation in glioblastoma [A sys…
  5. MGMT inhibition regulates radioresponse in GBM, GSC, and melanoma.
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Clinical Trials

Most Relevant Clinical Trials

  1. Impact of O6-methylguanine-DNA Methyltransferase (MGMT) Promoter Methylation and MGMT Expression on …
  2. Phase-1 Study of Folinic Acid to Modulate MGMT Gene in Glioblastoma
  3. Assessment of MGMT Promoter Methylation in Advanced Ewing Sarcoma Treated With Temozolomide and Irin…
  4. Comparison of Different Methods to Test MGMT Status in Glioblastoma Patients
  5. TMZ + Olaparib for MGMT Hypermethylated Colorectal Cancer
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