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(e.g. Fatty acid metabolic process, Pseudomonas infection, Kidney, DNA fingerprint, PPARA)
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QuickView for MLKL (gene)


Body Atlas

Most Correlated Tissues

  1. Parotid gland
  2. Bone marrow
  3. Lung
  4. Spleen
  5. Stomach pyloric
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Disease Atlas

Most Correlated Diseases

  1. Rhinitis
  2. Disease due to Orthopoxvirus
  3. Severe acute respiratory syndrome
  4. Cytomegalovirus infection
  5. Viral disease
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Pharmaco Atlas

Most Correlated Compounds

  1. KDELR1 protein, human
  2. BODIPY
  3. mitomycin D
  4. myelin oligodendrocyte glycoprotein
  5. Aclarubicin
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. Pdgfrb
  2. MUS81
  3. CUL3
  4. MAP3K4
  5. SGCB
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. MLKL Protects Pulmonary Endothelial Cells in Acute Lung Injury.
  2. MLKL overexpression leads to Ca2+ and metabolic dyshomeostasis in a neuronal cell model.
  3. Death at a funeral: Activation of the dead enzyme, MLKL, to kill cells by necroptosis.
  4. MLKL promotes hepatocarcinogenesis through inhibition of AMPK-mediated autophagy.
  5. Saracatinib inhibits necroptosis and ameliorates psoriatic inflammation by targeting MLKL.
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Clinical Trials

Most Relevant Clinical Trials

  1. Birinapant and Intensity Modulated Re-Irradiation Therapy in Treating Patients With Locally Recurren…
  2. Personalized Prevention of Colorectal Cancer Trial
  3. Aspirin in Preventing Colorectal Cancer in Patients With Colorectal Adenoma
  4. MORPHEE : Mechanisms of Cell Death Induced by Extracorporeal Photochemotherapy
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