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MYC
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NextBio Summary
General Info
Body Atlas
Most Correlated Tissues
B lymphocyte (IgM memory) of spleen
Vena cava
Granulocyte-macrophage progenitor cell of bone marrow
B lymphocyte (naive) of spleen
Omental adipose tissue
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Disease Atlas
Most Correlated Diseases
Hyperoxia
Whipple's disease
Physical activity
Irritable bowel syndrome
B-cell lymphoma
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Pharmaco Atlas
Most Correlated Compounds
CEP 14083
microcystin RR
FGF10 protein, human
Quinacrine
N-methylpyrrolidone
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Knockdown Atlas
Most Correlated Gene Perturbations
Bcl6
MIR141
KAT5
PRKDC
MAP2K7
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Curated Studies
Most Correlated Studies
Cancer Gene Census - mutations in cancer genes
Ovarian HEY cells overexpressing miR-141, miR-200b or miR-205 or with ZEB1 and WNT5A siRNA knockdown
Ovarian cancer HEY cells transfected to express MIRN205 microRNA
Ovarian cystadenocarcinoma HEY cells with overexpression of miR141
Livers of rat exposed to variety of hepatotoxic compounds
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Literature
Most Relevant Literature
Transcriptional regulation of microsomal prostaglandin E synthase 1 by the proto-oncogene, c-myc, in…
Cooverexpression of EpCAM and c-myc genes in malignant breast tumours.
Expression of C-myc and β-catenin and their correlation in triple negative breast cancer.
Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-te…
Generation of precursor, immature, and mature murine B1-cell lines from c-myc/bcl-xL-overexpressing …
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Clinical Trials
Most Relevant Clinical Trials
Dose-adjusted EPOCH-R in MYC Positive DLBCL
Phase Ib/2, Multicenter, Dose Escalation Study of DCR-MYC in Patients With Hepatocellular Carcinoma
Phase I, Multicenter, Dose Escalation Study of DCR-MYC in Patients With Solid Tumors, Multiple Myelo…
Study to Evaluate the Efficacy and Safety of CUDC-907 in Patients With RR DLBCL, Including Patients …
BAY 1000394 for MCL-1-, MYC-, and CCNE1-Amplified Tumors
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