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Maprotiline
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
HRH1
PPP2CA
AMHR2
CYP51A1
HMGCS1
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Pathway Enrichment
Most Correlated Biogroups
LEE_BMP2_TARGETS_DN
response to organic substance
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP
DODD_NASOPHARYNGEAL_CARCINOMA_DN
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
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Curated Studies
Most Correlated Studies
Broad Connectivity Map (CMAP 2.0) compound database
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
Hearts of rats exposed variety of toxicants
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Literature
Most Relevant Literature
Further studies on anti-inflammatory activity of maprotiline in carrageenan-induced paw edema in rat…
Mechanism of maprotiline-induced apoptosis: role of [Ca2+](i), ERK, JNK and caspase-3 signaling path…
Role of prefrontal cortical calcium independent phospholipase A₂ in antidepressant-like effect of ma…
Complex visual disturbances during maprotiline treatment.
Central and peripheral anti-inflammatory effects of maprotiline on carrageenan-induced paw edema in …
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Clinical Trials
Most Relevant Clinical Trials
A Study of Maprotiline in Combination With Tamoxifen and Temozolomide for Recurrent Glioblastoma
Biomarkers of ANTidepressant RESponse and Development Risk of Bipolar Disorder
A Study of Chinese Medicine Treating Depression
Pharmacovigilance in Gerontopsychiatric Patients
Evaluation of QTc Interval by Continuous Holter ECG Recording in Antipsychotic Drug-treated Patients…
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